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| Product Name | ML 347 |
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| Description | Potent and selective ALK2 and ALK1 inhibitor (IC50 values are 32 and 46 nM, respectively); displays >200 fold selectivity over ALK3 and ALK6 and >400 fold selectivity over VEGF2. Exhibits no activity at ALK4, ALK5 or in a panel of related kinases. Inhibits BMP4 signaling in a functional assay (IC50 = 152 nM). Purity 98%. MW (observed): 352.39 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-[6-(4-Methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline. LDN 193719, 1lWY, VU0469381 |
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| Gene, Accession, CAS # | CAS: 1062368-49-3 |
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| Catalog # | 4945/10 |
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| Price | |
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| Order / More Info | ML 347 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26678910 |
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| 产品资料 |
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