| 产品详情 |
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| Product Name | TRPV4 Antagonist I, RN-1734 |
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| Description | Purity ~95% (HPLC). A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4a-PDD-stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9uM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30uM). Formula: C14H22Cl2N2O2S Molecular Weight: 353.3 Solubility: DMSO (50mg/ml, pale yellow solution) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TRPV4 Antagonist I, RN-1734 (2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217852 |
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| Order / More Info | TRPV4 Antagonist I, RN-1734 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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