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| Product Name | Visinin-like protein-1, Recombinant Human (VSNL1, VILIP-1) |
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| Description | Purity ~95 % by SDS-PAGE Purified by immunoaffinity chromatography. Endotoxin: ≤1.0EU/ug (LAL). Visinin-like protein-1, also known as VILIP-1, belongs to a family of neuronal calcium sensor proteins. VILIP-1 is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Also, it is expressed in pancreatic beta-cells. VILIP-1 elevation enhances insulin secretion in cAMP-associated manner. Down-regulation of VILIP-1 decreased cAMP accumulation but increased insulin gene transcription. Recombinant human Visinin-like protein-1 , expressed in E. coli and purified by using conventional chromatography. Recombinant protein corresponding to aa1-191 of human Visinin-like protein-1 expressed in E. coli (NP_003376) Amino Acid Sequence: MGKQNSKLAP EVMEDLVKST EFNEHELKQW YKGFLKDCPS GRLNLEEFQQ LYV |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_003376 |
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| Catalog # | V2124-26 |
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| Order / More Info | Visinin-like protein-1, Recombinant Human (VSNL1, VILIP-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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