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| Product Name | Glyoxalase I, Recombinant, Human, aa1-184 |
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| Description | Purity ~90% (SDS-PAGE). GLO1 is involved in the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutathione. GLO1 is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. GLO1 enzyme is abundantly expressed and present in numerous tumor cell lines, in which its concentration is often upregulated ubiquitously. GLO1 is a major susceptible gene for autism in an ethnic Chinese population from Taiwan. GLO1 might be involved in the pathophysiology of mood disorders. GLO1 plays a role in the pathophysiology of mood disorders. Overexpression of GLO1 is associated with kidney tumor. Source: Recombinant protein corresponding to aa1-184 from human Glyoxalase I, expressed in E. coli. Molecular Weight: ~20.7kD (184aa, aa1-184) Specific Activity: >0.4units/mg. One unit will form 1.0umol of S-lactoylglutathione from methylglyoxal and reduced glutathione/minute at pH 7.5, at 25°C. Unit Definition: MAEPQPPSGG LTDEAALSCC SDADPSTKDF L |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Glyoxalase I, Recombinant, Human, aa1-184 (Lactoylglutathione lyase, Glx 1, GLO-1 Methylglyoxalase, Aldoketomutase) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 169981 |
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| Order / More Info | Glyoxalase I, Recombinant, Human, aa1-184 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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