| 产品详情 |
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| Product Name | Pregnane X Receptor |
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| Description | Highly Purified. EQFAITLKSYIECNR, from the internal region of human PXR. Control peptide corresponding to polyclonal antibody, Catalog#P6001-30A, goat x human. This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. Applications: Suitable for use in ELISA. Recommended Diltuions: Optimal dilutions to be determined by the rese |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Pregnane X Receptor (PXR, BXR, Nuclear Receptor Subfamily 1 Group I Member 2, NR1I2, ONR1, PAR1, PAR2, PAR, PARq, PRR, SAR, Steroid and Xenobiotic Receptor, SXR) (Control Peptide) |
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| Gene, Accession, CAS # | Accession: NP_003880.3; NP_071285.1; NP_148934.1 |
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| Catalog # | P6001-30A-P |
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| Order / More Info | Pregnane X Receptor from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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