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| Product Name | S100B, Recombinant, Human, aa1-92 (S100beta) |
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| Description | Purity ~95% (SDS-PAGE). S100B, previously called S100beta, belongs to the S100 family within the EF-hand superfamily of Ca2+ binding proteins (1-3). S100 proteins contain two EF-hand motifs that differ in affinity, separated by a hinge region with a hydrophobic cleft that is exposed upon Ca2+ binding (4). S100B is a 91 amino acid (aa) protein, after removal of the initial methionine, and is found as homodimers of 10.4kD monomers. Human S100B shares 99%, 98%, 100%, 99% and 97% aa sequence identity with mouse, rat, rabbit, equine and bovine S100B, respectively. Within the S100 family, human S100B shows the highest aa identity (59%) with S100A1. S100B is expressed primarily by astrocytes and oligodendrocytes in the central nervous system, and by Schwann cells in the peripheral nervous system (5). Ca2+-bound S100B interacts in vitro with at least 20 cytoplasmic proteins, including several structural molecules such as tubulin and GFAP (1, 4). It can inhibit the phosphorylation of these kina |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P04271 |
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| Catalog # | 145830 |
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| Order / More Info | S100B, Recombinant, Human, aa1-92 (S100beta) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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