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| Product Name | Granulocyte Macrophage Colony Stimulating Factor, Recombinant, Human |
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| Description | Purity ≥95% by SDS PAGE. Human GM-CSF is a 14.6kD globular protein consisting of 128 amino acid containing two dislufied bonds. GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. Recombinant human GM-CSF was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Molecular Weight: 14.6kD (128 amino acids) Sequence: MAPARSPSPS/ TQPWEHVNAI/ QEARRLLNLS/ RDTAAEMNET/ VEVISEMFDL/ QEPTCLQTRL/ ELYKQGLRGS/ LTKLKGPLTM/ MASHYKQHCP/ PTPETSCATQ/ IITFESFKEN/ LKDFLLVIPF/ DCWEPVQE Biological Activity: The ED50 for this effect is < 0.18 ng/ml. Measured in a cell proliferation |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Granulocyte Macrophage Colony Stimulating Factor, Recombinant, Human (GM-CSF, Burst Promoting Activity, CMCSF, Colony Stimulating Factor 2, CSF Alpha, Eosinophil Colony Stimulating Factor, Granulocyte Macrophage Colony Stimulating Factor, Molgramostin, Pluripoietin Alpha, Sargramostim) |
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| Gene, Accession, CAS # | Accession: NP_034099 |
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| Catalog # | G8950-33 |
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| Order / More Info | Granulocyte Macrophage Colony Stimulating Factor, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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