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| Product Name | Granulocyte-Macrophage Colony-Stimulating Factor, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). GM-CSF is a hematopoietic growth factor that is produced by endothelial cells, monocytes, fibroblasts and T-lymphocytes following their activation by antigens or mitogens. GM-CSF stimulates the development of macrophages and neutrophils and plays a role in the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. Approximately 90% of the secreted colony stimulating activities are due to GM-CSF. While non-glycosylated and glycosylated GM-CSF show similar activities in vitro, fully glycosylated GM-CSF is biologically more active in vivo compared to its non-glycosylated counterpart. Human and murine GM-CSF are species-specific and therefore, exhibit no cross-reactivity. Recombinant Human GM-CSF is a non-glycosylated, monomeric protein that contains intra-chain disulfide bonds. Source: Recombinant protein corresponding to human GM-CSF expressed in E. coli. Molecular Weight: ~15kD Biological Activity: The ED50 as determined by the dose-dependent |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Granulocyte-Macrophage Colony-Stimulating Factor, Recombinant, Human (GM-CSF, CSF-2, Pluripoietin-Alpha, Granulocyte Macrophage Colony Stimulating Factor) |
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| Gene, Accession, CAS # | SwissProt: P04141 |
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| Catalog # | 500045 |
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| Order / More Info | Granulocyte-Macrophage Colony-Stimulating Factor, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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