| 产品详情 |
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| Product Name | WT1, Recombinant, Human, aa147-446, His-Tag (Wilms Tumor Protein) |
| Description | Purity ~90% (SDS-PAGE). Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. Source: Recombinant protein corresponding to aa147-446 from human Wilms Tumor Protein, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~38.2kD AA |
| Size | 10ug, 50ug, 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | WT33 |
| Gene, Accession, CAS # | SwissProt: P19544 |
| Catalog # | 375877 |
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| Order / More Info | WT1, Recombinant, Human, aa147-446, His-Tag (Wilms Tumor Protein) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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