| 产品详情 |
| Edit |   |
|---|
| Product Name | TLR1/TLR2 Antagonist, CU-CPT22 |
|---|
| Description | Purity ~98% (HPLC). A cell-permeable benzotropolone compound that competes against Pam3CSK4- for TLR1/TLR2 heterodimer binding (Ki = 410nM) and selectively antagonizes against Pam3CSK4-induced RAW264.7 cellular NO production (IC50 = 580nM) without apparent cytotoxicity (up to 100uM and 24h). Exhibits no antagonist activity toward TLR2/TLR6, TLR3, TLR4, TLR7 at 0.5uM and little inhibitory potency against a panel of 10 kinases at 5uM (by <11% inhibition). Solubility: DMSO Primary Target: TLR1 Molar Mass: 362.4 |
|---|
| Size | 10mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | TLR1/TLR2 Antagonist, CU-CPT22 (Hexyl-3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 217836 |
|---|
| Price | |
|---|
| Order / More Info | TLR1/TLR2 Antagonist, CU-CPT22 from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|