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| Product Name | Plasminogen, active (PLG), Recombinant, Human |
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| Description | Purity ≥95% as determined by SDS-PAGE and HPLC. Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. (ECO:0000269|PubMed:14699093).; Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo. (ECO:0000269|PubMed:14699093). Biological Activity: Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells in vitro an |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | EC 3.4.21.7 |
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| Gene, Accession, CAS # | PLMN_HUMAN, SwissProt: P00747 |
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| Catalog # | 348197 |
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| Order / More Info | Plasminogen, active (PLG), Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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