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| Product Name | Fatty Acid Binding Protein 4, Recombinant, Human (FABP4, A-FABP) |
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| Description | Purity ≥ 90% (SDS-PAGE); Two-step procedure using size exclusion chromatography before and after refolding. Adipocyte fatty acid binding protein FABP4 is a 15kD member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds (bile acids or retinoids) in an internal cavity. FABP4 is expressed in a differentiation-dependent fashion in adipocytes and is a critical gene in the regulation of the biological function of these cells. In mice, targeted mutations in FABP4 provide significant protection from hyperinsulinemia and insulin resistance in the context of both dietary and genetic obesity. Adipocytes obtained from FABP4-deficient mice also have reduced efficiency of ipolysis in vitro and in vivo, and these mice exhibited moderately improved systemic dyslipidemia. Recent studies also demonstrated FABP4 expression in macrophages upon differentiation and activation. In these cells, FABP4 modulates inflammatory re |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001433 |
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| Catalog # | F0019-82D |
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| Order / More Info | Fatty Acid Binding Protein 4, Recombinant, Human (FABP4, A-FABP) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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