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| Product Name | Glutathione S-transferase omega 1, 140D alanine-to-aspartate variant, Recombinant, Human |
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| Description | Purity ≥95% (SDS-PAGE). Recombinant GSTO1 140D comprises a 241 amino acid fragment (1-241) corresponding to the GSTO1 140D mutant mature protein, which is expressed in E. coli with an amino-terminal hexahistidine tag. GSTO1 is a member of the theta class glutathione S- transferase-like (GSTTL) protein family. GSTO1 is expressed in a wide range of human tissues and exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities and also catalyzes the reduction of monomethylarsonate, an intermediate in the pathway of arsenic biotransformation. GSTO1 protects from oxidative stress, a risk factor for Alzheimer disease, vascular dementia and stroke. Several polymorphisms in the coding regions of the human GSTO1 have been identified. A polymorphism causing an alanine-to-aspartate (A140D) substitution in amino acid 140 produces a variant with lowered enzyme activities in the arsenic biotransformation. Applications: Suitable for use in ELISA. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Glutathione S-transferase omega 1, 140D alanine-to-aspartate variant, Recombinant, Human (GSTTL p28, Glutathione transferase omega, Gutathione-S-transferase like, Monomethyl Arsenous Reductase) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | G8135-21C |
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| Order / More Info | Glutathione S-transferase omega 1, 140D alanine-to-aspartate variant, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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