| 产品详情 |
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| Product Name | eEF2K Inhibitor, A-484954 |
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| Description | Purity ~98% (HPLC). A cell-permeable pyrido-pyrimidinedione derivative that acts as a highly potent and selective inhibitor of eukaryotic elongation factor-2 kinase (eEF2K) (IC50=280nM). Exhibits very little activity against a broad panel of serine/threonine and protein tyrosine kinases. Inhibits eEF2 phosphorylation in multiple cell lines tested without affecting the net eEF2 levels. At concentration where it inhibits eEF2K activity, it has no effect on the proliferation of cancer cell lines. Formula: C13H15N5O3 Molecular Weight: 289.3 Solubility: DMSO (2.5mg/ml, clear, colorless solution) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | eEF2K Inhibitor, A-484954 (7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide, Eukaryotic Elongation Factor-2 Kinase Inhibitor, A-484954) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217334 |
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| Order / More Info | eEF2K Inhibitor, A-484954 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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