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| Product Name | IL36RN, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Human IL36RN (IL1F5) is one of the cytokines from the interleukin 1 family encoded by a cluster of genes on chromosome 2. All members of this family show a 12 beta -strand, beta -trefoil configuration. IL36RN is a secreted protein monomer which is also known as interleukin 36 receptor antagonist (IL36RA). This cytokine is predominantly expressed in keratinocytes and a variety of other cell types including brain leukocytes, dendritic cells and macrophage cell types. IL36RN has shown increased expression in lesional psoriasis skin and is thought to play a role in skin inflammation. IL1F5 is a specific antagonist of the IL1 receptor related protein 2 - mediated response to IL1F9. It is also known to specifically inhibit the activation of NF-Kappa-B transcription factor which is induced by IL1F6. Source: Recombinant protein corresponding to human IL36RN expressed in E. coli. Endotoxin: <1EU/ug (LAL) |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL36RN, Recombinant, Human (IL36RN FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3, Interleukin-36 Receptor Antagonist Protein) |
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| Gene, Accession, CAS # | Gene ID: 26525, SwissProt: Q9UBH0 |
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| Catalog # | 500160 |
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| Order / More Info | IL36RN, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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