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| Product Name | IL36RN, Recombinant, Human, aa1-155, His-SUMO-Tag (Interleukin-36 Receptor Antagonist Protein) |
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| Description | Purity ~90% (SDS-PAGE). Inhibits the activity of interleukin-36 (IL36A, IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR. Source: Recombinant protein corresponding to aa1-155 from human IL36RN, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~33kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FIL1 deltaIL-1-related protein 3, IL-1RP3Interleukin-1 HY1, IL-1HY1Interleukin-1 delta, IL-1 deltaInterleukin-1 family member 5, IL-1F5 Interleukin-1 receptor antagonist homolog 1, IL-1ra homolog 1Interleukin-1-like protein 1, IL-1L1 |
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| Gene, Accession, CAS # | SwissProt: Q9UBH0 |
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| Catalog # | 373823 |
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| Order / More Info | IL36RN, Recombinant, Human, aa1-155, His-SUMO-Tag (Interleukin-36 Receptor Antagonist Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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