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| Product Name | IL2RA, Recombinant, Human |
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| Description | Purity ~98% (SDS-PAGE and HPLC). The IL-2 receptor system consists of three non-covalently linked subunits termed IL-2Ra, IL-2Rb, and IL-2Rg. The IL-2Ra is a type I transmembrane protein consisting of a 219aa extracellular domain, a 19aa transmembrane domain and a 13aa intracellular domain, which is not involved in the transduction of IL-2 signals. Proteolytic processing of IL-2Ralpha releases the entire extracellular domain of IL-2Ralpha thereby generating a 219aa soluble protein called soluble IL-2Ra (sIL-2Ra). The homodimeric form binds IL-2 (KD=10nM) and facilitates IL-2 signaling. The secreted sIL-2Ra is expressed on leukemia cells, lymphoma cells, newly activated T and B cells, as well as on approximately 10% of NK cells. Recombinant human sIL-2Ra is a 24.8kD protein containing 219aa consisting of only the extracellular domain of IL-2Ra. Due to glycosylation, IL-2Ra has an approximate molecular weight of 31kD based on SDS-PAGE gel and Mass Spectrometry. Source: Recombinant protei |
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| Size | 5ug, 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL2RA, Recombinant, Human (Interleukin-2 Receptor Subunit alpha, IL-2 Receptor Subunit alpha, IL-2-RA, IL-2R Subunit alpha, IL2-RA, TAC Antigen, p55, CD25) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149628 |
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| Order / More Info | IL2RA, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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