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| Product Name | IL-36RA, Recombinant, Human |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. The IL-1 family is comprised of 11 structurally related ligands,including the recently re-named IL-36RA (IL-1F5), IL-36alpha (IL-1F6), IL-36beta(IL-1F8), and IL-36gamma (IL-1F9). The interaction of IL-36 ligands with theIL-1Rrp2 receptor (IL-1R6) can induce various activities, including dendriticcell maturation and activation. IL-36RA can antagonize the NF-kappaB signalinginduced by either IL-36alpha, -beta or -gamma by binding to the IL-1Rrp2 receptor in amanner that prevents the initiation of functional signaling. Recombinant human IL-36RAis an E. coli derived 17kD proteincontaining 154 amino acid residues. Biological Activity: Measured by its ability to inhibit IL-36gamma; induced IL-6 production by human PBMCs. AA Sequence: VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAEKVIKGEE ISVVPNRALD ASLSPVILGV QGGSQCLSCG TEKGPILKLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFL CTSPEADQPV RLTQIPEDPA WDAPITDFYF QQCD Quality Control: Verified by N-terminal and M |
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| Size | 5ug, 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-36RA, Recombinant, Human (FIL1 delta, IL-1F5, IL-1HY1, IL-1L1, IL-1RP3, IL-1ra Homolog 1, IL-1, delta) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143405 |
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| Order / More Info | IL-36RA, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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