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| Product Name | SREBF1, GST-Tag, Recombinant (SREBP1, bHLHd1, SREBP-1c, Sterol Regulatory Element-Binding Protein 1) |
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| Description | Lysate. This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. Source: Partial length protein corresponding to of SREBF1, fused to GST-Tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SREBF1, Gene ID: 6720, Accession: NP_004167.3, SwissProt: P36956 |
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| Catalog # | 501020 |
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| Order / More Info | SREBF1, GST-Tag, Recombinant (SREBP1, bHLHd1, SREBP-1c, Sterol Regulatory Element-Binding Protein 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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