| 产品详情 |
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| Product Name | TMEM16A Inhibitor, T16Ainh-A01 |
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| Description | Purity ~97% (HPLC). An aminophenylthiazole that acts as an inhibitor of TMEM16A channel, a calcium-activated chloride channel (CaCC) (IC50=1.1uM). Fully blocks CaCC current in salivary gland cells at 10uM, but has very little effect in airway and intestinal cells, which is consistent with the observation of RNAi knock-down. Completely blocks chloride currents produced by TMEM16A Activator, Eact at 10uM. In addition, shown to block calcium-activated chloride channels in vascular smooth muscle cells, and relaxes murine and human blood vessels. Formula: C19H20N4O3S2 Molecular Weight: 416.5 Solubility: DMSO (100mg/ml, clear, colorless solution) |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TMEM16A Inhibitor, T16Ainh-A01 (2-(5-ethyl-4-hydroxy-6-methylpyrimidin-2-ylthio)-N-(4-(4-methoxyphenyl)thiazol-2-yl)acetamide, ANO1 Inhibitor, T16Ainh-A01, TMEM16A Antagonist, T16Ainh-A01) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217840 |
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| Order / More Info | TMEM16A Inhibitor, T16Ainh-A01 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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