| 产品详情 |
| Edit |   |
|---|
| Product Name | GASP-1, Recombinant, Human (GDF-associated serum protein-1, GASP, KIAA0443, WFIKKNRP) |
|---|
| Description | Purity ≥95% by SDS-PAGE gel and HPLC analyses. Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-beta binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin-A. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain. Recombinant human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66kD by SDS-PAGE analysis under non-reducing conditions. Biological Activity: Determined by its ability to inhibit human Myostatin (GDF-8) activity in MCP-11 cells. The ED50 for this effect is 0.0025-0.0040ug/ml in the presence |
|---|
| Size | 5ug, 25ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 143338 |
|---|
| Price | |
|---|
| Order / More Info | GASP-1, Recombinant, Human (GDF-associated serum protein-1, GASP, KIAA0443, WFIKKNRP) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|