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| Product Name | TANK, Recombinant, Human |
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| Description | Purity ~90% (SDS-PAGE). TANK, also known as TRAF (tumor necrosis factor receptor-associated Factor)-interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. Recombinant human TANK protein was expressed in E.coli and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa1-119 from human TANK, expressed in E.coli. Molecular Weight: ~13.6kD (MALDI-TOF) Applications: Suitable for use in SDS-PAGE. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TANK, Recombinant, Human (TRAF Family Member-associated NF-kappa-B Activator, TRAF-interacting Protein, I-TRAF, ITRAF, TRAF2) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 138412 |
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| Price | |
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| Order / More Info | TANK, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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