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| Product Name | TANK, Recombinant, Human, aa1-425, His-Tag |
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| Description | Purity ~85% (SDS-PAGE). TANK, also known as TRAF interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. Source: Recombinant protein corresponding to aa1-425 from human TANK at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~50.2kD (448aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDKNIGE QLNKAYEAFR QACMDRDSAV KELQQKTENY EQRIREQQEQ LSLQQTIIDK LKSQLLLVNS TQDNNYGCVP LLEDSETRKN NLTLDQPQDK VISGIAREKL PKVRRQEVSS PRKETSARSL GSPLLHERGN IEKTFWDLKE EFHKICMLAK AQKDHLSKLN IPDTATETQC SVPIQCTDKT DKQEALFKPQ AKDDINRGAP SITSVTPRGL CRDEEDTSFE SLSKFNVKFP PMDNDSTFLH STPERPGILS PATSEAVCQE KFNMEF |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TANK, Recombinant, Human, aa1-425, His-Tag (TRAF Family Member-associated NFkappa-B Activator Isoform A, I-TRAF, TRAF2) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 138753 |
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| Order / More Info | TANK, Recombinant, Human, aa1-425, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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