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| Product Name | Tankyrase, Human (TRF1 interacting ankyrin-related ADP-ribose polymerase, TANK1) (Control Peptide) |
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| Description | Highly purified. A 17-aa Peptide sequence within the N-terminal (after the 1st poly-pro) domain of human TANK1. The 3'ends of chromosomes are capped with telomere sequences (TTAGGG; 6-26 nucleotides in length) by ribonucleoprotein telomerase during DNA replication. Telomerase is an unusual RNA-dependent DNA polymerase that uses and RNA component to specify the addition of telomere. The telomeric RNA contains a sequence complementary to TTAGGG. Introduction of telomerase into normal human cells has been shown to extend normal cell life by ~ 20 doubling. Poly(ADP-ribose) polymerases (PARPs) catalyze formation of long, branched chain of poly(ADP-ribose) onto protein acceptors using NAD+ as a substrate. Poly(ADP)ribosylation is a transient posttranslational modification that can either enhance or reduce protein activity. Tankyrase (TRF1 interacting ankyrin-related ADP-ribose polymerase; human 1327 aa, renamed as TNKS-1/TANK1, chromosome 8), a modular protein with homology to ankyrin and po |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T0900-06 |
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| Order / More Info | Tankyrase, Human (TRF1 interacting ankyrin-related ADP-ribose polymerase, TANK1) (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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