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| Product Name | TARDBP, Recombinant, Human, aa1-414, His-Tag (TAR DNA Binding Protein, ALS10, TDP43) |
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| Description | Purity ~90% (SDS-PAGE). TARDBP, as known as TAR DNA binding protein, was originally identified as a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. It has also been identified in individuals diagnosed with chronic traumatic encephalopathy, a condition that often mimics ALS and that has been associated with athletes who have experienced multiple concussions and other types of head injury. It has been shown to bind both DNA and RNA and have multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation. Source: Recombinant protein corresponding to human TARDBP, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~48.8kD (450aa) AA Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSEY IRVTEDENDE PIEIPSEDDG TVLLSTVTAQ FPGACGLRYR NPVSQCMRGV RLVEGILHAP DAGWGNLVYV VNYPKDNKRK MDETDASSAV KVKRAVQKTS DLIVLGLPWK TTEQDLKEYF STFGEVLMVQ VKKDLKTGHS KGFGFVRFTE YETQVKVMSQ RHMIDGRWCD CKLPNSKQSQ |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137225 |
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| Order / More Info | TARDBP, Recombinant, Human, aa1-414, His-Tag (TAR DNA Binding Protein, ALS10, TDP43) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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