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| Product Name | Synuclein, alpha, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Alpha-Synuclein (aa1-140), an acidic neuronal protein of 140 aa, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. Alpha- synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Moreover, recent studies have shown that Alpha-synuclein has chaperone activity and that this activity is lost upon removing its C-terminal acidic tail (amino acids 96-140). Sequences of Amino Acids: MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA Molecular Weight: ~14.4kD |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Synuclein, alpha, Recombinant, Human (Alpha-synuclein, SNCA, MGC110988, Non-A beta Component of AD Amyloid, Non-A4 Component of Amyloid Precursor, NACP, PARK1, PARK4, PD1) |
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| Gene, Accession, CAS # | Accession: NP_000336 |
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| Catalog # | S9500-01P |
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| Order / More Info | Synuclein, alpha, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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