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| Product Name | UFD1L, Recombinant, Human, aa1-307, GST-Tag (Ubiquitin Fusion Degradation Protein 1 Homolog) |
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| Description | Purity ~90% (SDS-PAGE). Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures. Source: Recombinant protein corresponding to aa1-307 from human UFD1L, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~61.5kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q92890 |
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| Catalog # | 375762 |
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| Order / More Info | UFD1L, Recombinant, Human, aa1-307, GST-Tag (Ubiquitin Fusion Degradation Protein 1 Homolog) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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