| 产品详情 |
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| Product Name | UGT1A1, Recombinant, Human, aa26-533, His-Tag (UDP-Glucuronosyltransferase 1-1) |
| Description | Purity ~90% (SDS-PAGE). UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1. Source: Recombinant protein corresponding to aa26-533 from human UGT1A1, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~59.1kD AA |
| Size | 10ug, 50ug, 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Bilirubin-specific UDPGT isozyme 1, hUG-BR1UDP-glucuronosyltransferase 1-A, UGT-1A, UGT1AUDP-glucuronosyltransferase 1A1 |
| Gene, Accession, CAS # | SwissProt: P22309 |
| Catalog # | 375766 |
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| Order / More Info | UGT1A1, Recombinant, Human, aa26-533, His-Tag (UDP-Glucuronosyltransferase 1-1) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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