| 产品详情 |
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| Product Name | BCMA,Fc, Recombinant, Human (B Cell Maturation Protein, CD269, TNFRSF17) |
| Description | Purity ~95% (SDS-PAGE) Endotoxin: ≤0.1EU/ug (LAL). BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. Its downstream signaling is dependent on NF-kappaB and JNK. Binds human and mouse BAFF and APRIL. Sequence T:he extracellular domain of human BCMA (aa2-54) is fused at the C-terminus to the Fc portion of human IgG1. Biological Activity: Blocks the binding of BAFF and APRIL to their receptors BCMA and TACI, inhibiting BAFF- and APRIL-mediated B cell activation. |
| Size | 50ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | B Cell Maturation Protein, CD269, TNFRSF17 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 44597 |
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| Order / More Info | BCMA,Fc, Recombinant, Human (B Cell Maturation Protein, CD269, TNFRSF17) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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