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| Product Name | RGS1, Recombinant, Human, aa1-209, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120aa motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Source: Recombinant corresponding to aa1-209 from human RGS1, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~26kD (233aa) confirmed by MALDI-TOF AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMRAAAI STPKLDKMPG MFFSANPKEL KGTTHSLLDD KMQKRRPKTF GMDMKAYLRS MIPHLESGMK SSKSKDVLSA AEVMQWSQSL EKLLANQTGQ NVFGSFLKSE FSEENIEFWL ACEDYKKTES DLLPCKAEEI YKAFVHSDAA KQINIDFRTR ESTAKKIKAP TPTCFDEAQK V |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | RGS1, Recombinant, Human, aa1-209, His-Tag (B Cell Activation Protein BL34, Early Response Protein 1R20, Regulator of G-protein Signaling 1, 1R20, BL34, IER1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45457 |
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| Order / More Info | RGS1, Recombinant, Human, aa1-209, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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