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| Product Name | ROCK1, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). ROCK1 is a ubiquitously expressed serine/threonine kinase that is a downstream target of the small GTPase RhoA. ROCK1 is involved in diverse cellular functions, including smooth muscle contraction, actin cytoskeleton organization, cell adhesion and motility, and gene expression. ROCK1 contributes to the development of cardiac fibrosis and induction of fibrogenic cytokines in cardiomyocytes in response to pathological stimuli. ROCK1 knockout mice exhibit reduced perivascular and interstitial fibrosis which is associated with reduced expression of a variety of extracellular matrix (ECM) proteins and fibrogenic cytokines. Source: Recombinant protein corresponding to human ROCK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~85kD Specific Activity: 65nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ROCK1, Recombinant, Human, GST-Tag (Rho-associated Protein Kinase 1, Renal Carcinoma Antigen NY-REN-35, Rho-associated, Coiled-coil-containing Protein Kinase 1, P160ROCK, ROCK-I, ROKbeta) |
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| Gene, Accession, CAS # | Accession: NM_005406 |
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| Catalog # | 500426 |
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| Order / More Info | ROCK1, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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