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| Product Name | PPM1A, Recombinant, Human, aa1-382, GST-Tag (Protein Phosphatase 1A) |
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| Description | Purity ~90% (SDS-PAGE). Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB. Source: Recombinant protein corresponding to aa1-382 from human PPM1A, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~69.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Protein phosphatase 2C isoform alpha |
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| Gene, Accession, CAS # | SwissProt: P35813 |
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| Catalog # | 374816 |
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| Order / More Info | PPM1A, Recombinant, Human, aa1-382, GST-Tag (Protein Phosphatase 1A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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