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| Product Name | Secretase, beta Activity BioAssay™ Kit (Fluorometric) |
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| Description | β-Secretase has been implicated to be an excellent target for anti-amyloid therapy for the treatment of Alzheimer's disease. Sample Type: Cell and tissue lysates, culture media, urine, plasma and serum, as well as many other biological fluids Intended Use: Convenient fluorescence method for detecting beta-secretase activity in biological and purified samples. Test Principle: The beta-Secretase activity BioAssay™ Kit provides a convenient fluorescence method for detecting beta-secretase activity in biological and purified samples. The assay utilizes a secretase-specific peptide conjugated to two reporter molecules EDANS and DABCYL. In the uncleaved form, the fluorescent emissions from EDANS are quenched by the physical proximity of the DABCYL moiety. Cleavage of the peptide by secretase physically separates EDANS and DABCYL allowing for the release of a fluorescent signal. The level of secretase enzymatic activity in samples is proportional to the level of fluorescence intens |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 167959 |
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| Order / More Info | Secretase, beta Activity BioAssay™ Kit (Fluorometric) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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