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| Product Name | SHH, Recombinant, Mouse (Sonic Hedgehog Protein, HHG-1) |
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| Description | Purity ~95% (SDS-PAGE). Mouse SHH is part of a small group of secreted proteins that are vital for development in both vertebrates and invertebrates. Mouse SHH shares 99% homology with the human gene for SHH. Sonic HedgeHog is a protein that is vital in guiding the early embryo; it has been associated as the major inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. SHH binds to the patched receptor to activate the transcription of target genes. Sonic HedgeHog also regulates another factor, the gli oncogene. Recombinant Mouse SHH is a single, non-glycosylated polypeptide chain of 19.8kD. Source: Recombinant protein corresponding to mouse SHH expressed in E. coli. Molecular Weight: ~19.8kD Biological Activity: The ED50 of this protein, as measured by its ability to induce alkaline phosphatase production in mouse myoblast cell, was in the range of 500ng-3ug/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 25ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q62226 |
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| Catalog # | 500448 |
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| Order / More Info | SHH, Recombinant, Mouse (Sonic Hedgehog Protein, HHG-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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