| 产品详情 |
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| Product Name | Threonine Dehydrogenase Inhibitor, QC1 |
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| Description | Purity ~96% (HPLC). A cell-permeable quinazolinecarboxamide (QC) compound that acts as a potent, reversible and mixed noncompetitive inhibitor of threonine dehydrogenase activity (IC50 ~ 0.5uM for mTDH) with excellent selectivity over hydroxysteroid, alcohol, lactate, or glucose-6-phosphate dehydrogenases (IC50 >10uM). Shown to block threonine catabolism, induce autophagy and impede the growth of highly proliferating mouse embryonic stem cells (mESCs; EC50 ~3uM) with no effect on ESCs-derived embryoid body cells, 3T3 fibroblasts or tumor cells (EC50 ~1 mM). Formula: C23H16F3N3O2S Solubility: DMSO Molar Mass: 455.5 |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Threonine Dehydrogenase Inhibitor, QC1 (N-Benzyl-4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroquinazoline-7-carboxamide) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217832 |
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| Price | |
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| Order / More Info | Threonine Dehydrogenase Inhibitor, QC1 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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