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| Product Name | Threonyl t-RNA Synthetase, Recombinant, Human, His-Tag (PL-7, TARS) |
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| Description | Purity ~90% (SDS-PAGE). Threonyl-tRNA Synthetase is a member of the aminoacyl-tRNA synthetase family, key enzymes of protein biosynthesis which charge tRNA molecules with the respective amino acids. This 83kD protein is an autoantigen recognized by PL-7 antibodies which occur in a subset of patients with polymyositis and dermatomyositis. Preliminary data suggest that PL-7 antibodies (similar to Jo-1 antibodies) indicate an increased risk for lung involvement, but this needs to be confirmed for a larger number of cases. Source: Recombinant protein corresponding to human Threonyl-tRNA Synthetase, fused to 6x his-tag, expressed in Sf9 insect cells. Molecular Weight: ~83.31kD Specificity: Binds IgG-type human auto-antibodies Applications: Suitable for use in Western Blot with monoclonal anti-hexa-His-tag antibody & Polymyositis sera and standard ELISA test (checker-board analysis of positive/negative sera panels immuno-dot test). Suitable for biotinylation and iodination. |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209233 |
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| Order / More Info | Threonyl t-RNA Synthetase, Recombinant, Human, His-Tag (PL-7, TARS) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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