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| Product Name | SNURF, Recombinant, Human, aa1-71, His-Tag (SNRPN Upstream Reading Frame Protein) |
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| Description | Purity ~90% (SDS-PAGE). SNuRF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' uTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known. Source: Recombinant corresponding to |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_073715 |
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| Catalog # | 218578 |
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| Order / More Info | SNURF, Recombinant, Human, aa1-71, His-Tag (SNRPN Upstream Reading Frame Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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