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Antigenic Specificity | Chromogranin A |
Clone | LK2H10 |
Host Species | Mouse |
Reactive Species | human, nonhuman primate, porcine, rabbit, rat |
Isotype | IgG1, kappa |
Format | biotin conjugate |
Size | 500 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:10-1:100, Immunofluorescence: 1:10-1:100, Immunohistochemistry (Paraffin): 1:800, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Chromogranin A Monoclonal Antibody (LK2H10), Biotin. Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. |
Immunogen | n/a |
Other Names | SP-I, betagranin (N-terminal fragment of chromogranin A), chromogranin-A, parathyroid secretory protein 1, pituitary secretory protein I |
Gene, Accession # | Entrez: 100346049, 100766424, 1113, 24258, 397540; Uniprot: P04404, P10354, P10645 |
Catalog # | MA5-13093 |
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Order / More Info | Chromogranin A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 12446587, 12454818, 14586073, 14738320, 15316316, 15865613, 15958558, 16084457, 16552385, 17618455, 18038885, 18721831, 19047895, 19598001, 20216406, 21532524, 22301491, 22382924, 22422124, 22461520, 23354792, 23426123, 23465278, 23657976, 24628963 |
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