产品详情 |
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Antigenic Specificity | Chromogranin A |
Clone | PHE5 |
Host Species | Mouse |
Reactive Species | human, nonhuman primate |
Isotype | IgG1 |
Format | purified |
Size | 500 µl |
Concentration | n/a |
Applications | Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 0.5-1.0 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Chromogranin A Monoclonal Antibody (PHE5). Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. |
Immunogen | n/a |
Other Names | SP-I, betagranin (N-terminal fragment of chromogranin A), chromogranin-A, parathyroid secretory protein 1, pituitary secretory protein I |
Gene, Accession # | Entrez: 1113; Uniprot: P10645 |
Catalog # | MA5-13281 |
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Order / More Info | Chromogranin A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 12454818, 14738320, 16084457, 16552385, 19047895, 22301491, 22422124, 23426123, 23465278, 23657976, 24628963 |
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