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Antigenic Specificity | Chromogranin A |
Clone | SP12 |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | IgG |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:50-1:5000, Immunofluorescence: 1:50-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Western Blot: 1:500-1:5000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Chromogranin A Monoclonal Antibody (SP12). Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. |
Immunogen | n/a |
Other Names | SP-I, betagranin (N-terminal fragment of chromogranin A), chromogranin-A, parathyroid secretory protein 1, pituitary secretory protein I |
Gene, Accession # | Entrez: 1113, 24258; Uniprot: P10354, P10645 |
Catalog # | MA5-14536 |
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Order / More Info | Chromogranin A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 18386164, 21893434, 22344361, 22497861, 22741527, 24218309, 24399015, 27606145, 27688729 |
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