| 产品详情 |
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| Antigenic Specificity | ITGA4 / VLA-4 / CD49d |
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| Clone | MRalpha4-1 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG2a |
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| Format | fluorescein (FITC) conjugate |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:1 - 1:10), IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ITGA4 / VLA-4 / CD49d Antibody (clone MRalpha4-1, FITC) LS-C188416. Recognizes rat CD49d, otherwise known as integrin alpha 4 chain/VLA-4, a 150kD type-1 transmembrane glycoprotein and member of the integrin alpha chain family, which acts as a receptor for fibronectin and CD106 (VCAM-1). CD49d is expressed broadly on T and B lymphocytes, monocytes, thymocytes, mast cells and dendritic cells and is involved in cell-cell interactions, mononuclear cell trafficking to sites of endothelial inflammation, and the adhesion of cells to the extracellular matrix. Clone MRalpha4-1 inhibits the in vitro and in vivo functions of CD49d. Studies have shown that in rat Peyers patches, clone MRalpha4-1 inhibits the rolling and adherence of lymphocytes to postcapillary venules (PCV), and significantly inhibits the transendothelial migration of T lymphocytes. |
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| Immunogen | RBL-2H3 rat basophilic leukaemia cell line. |
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| Other Names | ITGA4, 269C wild type, CD49D, IA4, Integrin alpha-4, Integrin alpha 4, Integrin alpha-4 subunit, Integrin alpha-IV, VLA-4, VLA-4 subunit alpha, CD49d antigen |
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| Gene, Accession # | ITGA4, Gene ID: 3676 |
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| Catalog # | LS-C188416 |
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| Price | |
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| Order / More Info | ITGA4 / VLA-4 / CD49d Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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