| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | ITGA4 / VLA-4 / CD49d |
|---|
| Clone | MRalpha4-1 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | rat |
|---|
| Isotype | IgG2a |
|---|
| Format | phycoerythrin (RPE) conjugate |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | Flo (1:1), IP |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | ITGA4 / VLA-4 / CD49d Antibody (clone MRalpha4-1, RPE) LS-C188418. Recognizes rat CD49d, otherwise known as integrin alpha 4 chain/VLA-4, a 150kD type-1 transmembrane glycoprotein and member of the integrin alpha chain family, which acts as a receptor for fibronectin and CD106 (VCAM-1). CD49d is expressed broadly on T and B lymphocytes, monocytes, thymocytes, mast cells and dendritic cells and is involved in cell-cell interactions, mononuclear cell trafficking to sites of endothelial inflammation, and the adhesion of cells to the extracellular matrix. Clone MRalpha4-1 inhibits the in vitro and in vivo functions of CD49d. Studies have shown that in rat Peyers patches, clone MRalpha4-1 inhibits the rolling and adherence of lymphocytes to postcapillary venules (PCV), and significantly inhibits the transendothelial migration of T lymphocytes. |
|---|
| Immunogen | RBL-2H3 rat basophilic leukaemia cell line. |
|---|
| Other Names | ITGA4, 269C wild type, CD49D, IA4, Integrin alpha-4, Integrin alpha 4, Integrin alpha-4 subunit, Integrin alpha-IV, VLA-4, VLA-4 subunit alpha, CD49d antigen |
|---|
| Gene, Accession # | ITGA4, Gene ID: 3676 |
|---|
| Catalog # | LS-C188418 |
|---|
| Price | |
|---|
| Order / More Info | ITGA4 / VLA-4 / CD49d Antibody from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|