| 产品详情 |
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| Antigenic Specificity | BUB3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, human |
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| Isotype | n/a |
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| Format | Protein G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BUB3 Antibody LS-C498467. Specificity: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1. |
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| Immunogen | Recombinant human Mitotic checkpoint protein BUB3 protein (6-217AA) |
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| Other Names | BUB3, Budding uninhibited by benomyl, HBUB3, BUB3L, Mitotic checkpoint component |
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| Gene, Accession # | BUB3, Gene ID: 9184 |
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| Catalog # | LS-C498467 |
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| Price | |
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| Order / More Info | BUB3 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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