产品详情 |
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Antigenic Specificity | ATM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Cy7 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | FCM, IF(IHC-P), IF(ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ATM Polyclonal Antibody, Cy7 Conjugated. • Target Background: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a sing |
Immunogen | KLH conjugated synthetic peptide derived from mouse ATM. Immunogen Range: 2700-2750/3066 |
Other Names | AI256621; C030026E19Rik; Serine-protein kinase ATM; Ataxia telangiectasia mutated homolog; A-T mutated homolog; Atm |
Gene, Accession # | Gene ID: 11920, SwissProt: Q62388 |
Catalog # | bs-1370R-Cy7 |
Price | |
Order / More Info | ATM Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |
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