| 产品详情 |
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| Antigenic Specificity | Mannose Receptor / CD206 |
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| Clone | 7-450 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | affinity purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC, IHC-Fr (1:50 - 1:500) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mannose Receptor / CD206 Antibody (clone 7-450) LS-C58102. Specific for human CD206, otherwise known as macrophage mannose receptor (MMR), a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites. |
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| Immunogen | Monocyte-derived dendritic cells. |
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| Other Names | MRC1, BA541I19.1, CLEC13D, CD206, CD206 antigen, Macrophage mannose receptor 1, Mannose Receptor, Macrophage mannose receptor, MMR, Mannose receptor, C type 1, MRC1L1, CLEC13DL |
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| Gene, Accession # | MRC1, Gene ID: 4360 |
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| Catalog # | LS-C58102 |
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| Price | |
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| Order / More Info | Mannose Receptor / CD206 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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