| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CDC14B |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | peroxidase (HRP) conjugate |
|---|
| Size | 100ul |
|---|
| Concentration | 1ug/ul |
|---|
| Applications | IHC-P |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CDC14B Polyclonal Antibody, HRP Conjugated. • Target Background: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-direc |
|---|
| Immunogen | KLH conjugated synthetic peptide derived from human CDC14B. Immunogen Range: 94-122/498 |
|---|
| Other Names | CDC14B3; Cdc14B1; Cdc14B2; hCDC14B; Dual specificity protein phosphatase CDC14B; CDC14 cell division cycle 14 homolog B; CDC14B |
|---|
| Gene, Accession # | Gene ID: 8555, SwissProt: O60729 |
|---|
| Catalog # | bs-7608R-HRP |
|---|
| Price | |
|---|
| Order / More Info | CDC14B Antibody from BIOSS ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|