| 产品详情 |
| Edit |   |
|---|
| Product Name | HCV-NC 22 kDa protein |
|---|
| Description | HCV-NC 22 kDa (residues 2-192)- Biotin conjugated protein.The protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-192, with a molecularweight of 22 kDa and is biotin conjugated.The protein isfused to beta-galactosidase (114 kDa) at the N-terminus.Hepatitis C Virus core proteins are purified by proprietarychromatographic techniques.The hepatitis C virus (HCV) core protein represents thefirst 191 amino acids of the viral precursor polyproteinand is cotranslationally inserted into the membrane of theendoplasmic reticulum (ER)Hepatitis C virus (HCV) core is a viral structural protein;it also participates in some cellular processes, includingtranscriptional regulation. However, the mechanisms ofcore-mediated transcriptional regulation remain poorly understood. Hepatitis C virus (HCV) core protein is thoughtto contribute to HCV pathogenesis through its interactionwith various signal transduction pathwaysIn addition, HCV core antigen is a recently developedmarker of hepatitis C infection. It is remarkably efficientat establishing persistent infection, suggesting that it hasevolved one or more strategies aimed at evading the hostimmune response. T cell responses, including interferongamma production, are severely suppressed in chronicHCV patients. The HCV core protein has been previouslyshown to circulate in the bloodstream of HCV-infected patients and inhibit host immunity through an interaction withgC1qR. MW: 136 kDa. Purity >95% by SDS-PAGE |
|---|
| Size | 100 ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA, WB |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | orb97904 |
|---|
| Price | |
|---|
| Order / More Info | HCV-NC 22 kDa protein from BIORBYT LTD. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|