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| Antigenic Specificity | NECAB3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NECAB3 Polyclonal Antibody. The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
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| Immunogen | n/a |
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| Other Names | APBA2BP; EFCBP3; NIP1; STIP3; SYTIP2; XB51; dJ63M2.4; dJ63M2.5; EF-hand calcium binding protein 3; N-terminal EF-hand calcium-binding protein 3; Nek2-interacting protein 1; X11L-binding protein 51; amyloid beta (A4) precursor protein-binding; family A; member 2 binding protein; amyloid beta A4 protein-binding family A memb |
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| Gene, Accession # | Entrez: 63941; Uniprot: Q96P71 |
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| Catalog # | PA5-65389 |
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| Price | |
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| Order / More Info | NECAB3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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