| 产品详情 |
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| Antigenic Specificity | SUR1 |
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| Clone | S289-16 |
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| Host Species | Mouse |
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| Reactive Species | hamster, human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100, Immunofluorescence: Assay-Dependent, Immunohistochemistry (PFA fixed): 1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SUR1 Monoclonal Antibody (S289-16). The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, a |
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| Immunogen | n/a |
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| Other Names | AM60008PU-N, ABC36, Abcc8, ATP binding cassette sub family C member 8, HHF1, HRINS, MRP8, PHHI, SUR, SUR1, Sulfonylurea receptor (hyperinsulinemia), ATP binding cassette sub family C (CFTR/MRP) member 8, ATP binding cassette transporter sub family C member 8 (1), ATP-binding cassette sub-family C member 8, HI, PHHI, Sulfonylurea receptor 1, SUR1delta2, TNDM2 |
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| Gene, Accession # | Entrez: 100764394, 20927, 25559, 6833; Uniprot: Q09428, Q09429 |
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| Catalog # | MA5-27660 |
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| Price | |
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| Order / More Info | SUR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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