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Product Name | JNJ 10397049 |
Description | Selective OX2 receptor antagonist (pIC50 = 7.4 for chimeric OX2 receptors; pKB values are 5.9 and 8.5 for OX1 and OX2 receptors respectively). Shows no significant activity in a panel of over 50 other neurotransmitters and neuropeptide receptors. Achieves high level of OX2 receptor occupancy in the rat brain; exhibits sleep-promoting effects in rats. Purity 99%. MW (observed): 484.18 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-(2,4-Dibromophenyl)-N'-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]-urea |
Gene, Accession, CAS # | CAS: 708275-58-5 |
Catalog # | 4317/10 |
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Order / More Info | JNJ 10397049 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 25845696 |
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